To solve this issue, you can use perlbrew to install a lower version of Perl and run PennCNV on top of that without re-compilation. Perlbrew defaults the installation to non-threaded and non-multi perl versions. You may want to use "perlbrew install perl-thread -multi". See more instructions at the end of this page. There are two ways to use PennCNV in a Windows system: either install Cygwin and use PennCNV under Cygwin shell, or install ActivePerl and use PennCNV in a regular Windows command shell. These two methods are described in the following two sections. IMPORTANT NOTES: My recommendation to Windows users is that you just do these two things: (1) Install 32-bit Perl 5.8.8 from here. There is no need for compilation or any other complication. #ACTIVEPERL 5.12.3 FREE#īut if you do not have anything more challenging to do or if you just want to kill some time, then feel free to play the compilation game below. If you really like to use Windows, and if you do not want to use command line, you can alternatively try to use PennCNV inside BeadStudio software by the Universal CNV adapter. This works well for me, maybe there is something here you can use.You can access the webpage describing this procedure on using PennCNV Plug-in. #loops through required modules and installs them if missing #I've gotten into the habit of setting this on all my scripts, prevents weird path issues if the script is not being run by root This is what I do in some scripts on an Ubuntu (or debian server) #!/usr/bin/perl Seems like you've already got your answer but I figured I'd chime in. Print the script version and CPAN.pm version. Recompiles dynamically loaded modules with CPAN::Shell->recompile. List the modules by the specified authors. Module name, local version, and CPAN version. Modules locally installed but have newer versions on CPAN). This prints one line for each out-of-date module (meaning, Show the Changes files for the specified modules Shows the primary maintainers for the specified modules Here's a summary of the current features (which might be newer than the one that comes with CPAN.pm and perl): -aĬreates the CPAN.pm autobundle with CPAN::Shell->autobundle. There are several other things that you can do with the cpan tool as well. This works on Unix, Mac, and should be just fine on Windows (especially Strawberry Perl). If you don't give it any arguments it starts the CPAN.pm shell. Just give it the modules that you want to install and let it do it's work. This means that you can do the same thing as every other Perl user when it comes to installing modules, and things tend to "just work" a lot more often.Ī couple of people mentioned the cpan utility, but it's more than just starting a shell. It also includes some hard-to-compile Perl modules with their external C library dependencies, notably XML::Parser. This is a version of Perl that comes packaged with a pre-configured CPAN shell as well as a compiler. Nowadays, when I'm on a system with an old CPAN, the first thing I do is update the shell and set it up to do this so I can do most of my cpan work as a normal user.Īlso, I'd strongly suggest that Windows users investigate strawberry Perl. If you have an old CPAN shell, simply install the new cpan ("install CPAN") and when you reload the shell, it should prompt you to configure these new directives. This is much safer, since it means that tests don't run as root. That used to be necessary to install into the system directory, but modern versions of the CPAN shell allow you to configure it to use sudo just for installing. I note some folks suggesting one run cpan under sudo.
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Ideally, with constant reference to these facts-the bulk of which are undoubtedly yet to be discovered-theoretical population genetics begins by distilling everything into a workable mathematical model of genetic transmission within a species. A tremendous amount is known about the workings of organisms in their environments and about interactions among species. Its main purpose is to understand the ways in which the forces of mutation, natural selection, random genetic drift, and population structure interact to produce and maintain the complex patterns of genetic variation that are readily observed among individuals within a species. Theoretical population genetics is the mathematical study of the dynamics of genetic variation within species. It is valuable to define this field narrowly. Stepping into this future, it will be important to develop new approximations that reflect new data and not to let well-accepted models diminish the possibilities. In light of its many incarnations and befitting its ties to evolutionary biology, the limits of theoretical population genetics are recognized to be changing over time, with a number of new paths to follow. Arguably of more importance, theoretical population genetics underlies our knowledge of within-species variation across the globe and for all kinds of life. 2002) and the foundation for association studies, which aim to map the genes that cause human disease ( J orde 1995). Theoretical population genetics is the framework for studies of human history ( R eich et al. This 100-year-old field now sits close to the heart of modern biology. THE purpose here is to discuss the limits of theoretical population genetics. The design of geometric models for object shapes, in particular, is occasionally called computer-aided geometric design ( CAGD). Because of its enormous economic importance, CAD has been a major driving force for research in computational geometry, computer graphics (both hardware and software), and discrete differential geometry. The modern ubiquity and power of computers means that even perfume bottles and shampoo dispensers are designed using techniques unheard of by engineers of the 1960s. CAD is also widely used to produce computer animation for special effects in movies, advertising and technical manuals, often called DCC digital content creation. : 71, 106ĬAD is an important industrial art extensively used in many applications, including automotive, shipbuilding, and aerospace industries, industrial and architectural design ( building information modeling), prosthetics, and many more. As in the manual drafting of technical and engineering drawings, the output of CAD must convey information, such as materials, processes, dimensions, and tolerances, according to application-specific conventions.ĬAD may be used to design curves and figures in two-dimensional (2D) space or curves, surfaces, and solids in three-dimensional (3D) space. However, it involves more than just shapes. ĬAD software for mechanical design uses either vector-based graphics to depict the objects of traditional drafting, or may also produce raster graphics showing the overall appearance of designed objects. In mechanical design it is known as mechanical design automation ( MDA), which includes the process of creating a technical drawing with the use of computer software. Its use in designing electronic systems is known as electronic design automation ( EDA). The terms computer-aided drafting ( CAD) and computer-aided design and drafting ( CADD) are also used. CAD output is often in the form of electronic files for print, machining, or other manufacturing operations. : 4 Designs made through CAD software are helpful in protecting products and inventions when used in patent applications. : 3 This software is used to increase the productivity of the designer, improve the quality of design, improve communications through documentation, and to create a database for manufacturing. Computer-aided design ( CAD) is the use of computers (or workstations) to aid in the creation, modification, analysis, or optimization of a design. For pan sauces, add the wine after removing the cooked meat. In marinades, the wine goes in first along with the other ingredients.įor braises, stews and long-simmered sauces, the wine goes in early, just after cooking the vegetables and meat. However, some chefs will add a dash of a high-quality wine very near the end in some dishes - but you should only do this with a superior wine. Adding it in just before serving can be overpowering and it won’t have time to enhance the flavor in most dishes. When to Add Wine During Cookingįor most recipes, we add wine early in the cooking process. Another option is to buy boxed wine for cooking, which is stored in an airtight bag and can last for about six weeks. Measure one as you’re filling it so you’ll know later how much each frozen cube contains. Most ice tray cubes are about two tablespoons. One easy way to freeze wine for cooking is to use ice trays, then store the cubes in a plastic bag once they are frozen. If you want to use real wine in your cooking but won’t be able to drink the leftovers, you can freeze it and use in other dishes later. For the few extra dollars, use real wine, especially since most recipes only call for small amounts of it. The extra sodium and poor taste won’t improve the flavors of your dish - and could even ruin it. Manufacturers add on average a teaspoon of sodium per eight ounces of wine to extend the shelf life of cooking wine. Despite their convenience and lower costs, most chefs will advise to steer clear.Ĭooking wines contain no alcohol and are undrinkable due to their taste, preservatives and added sodium. If you don’t drink wine often, you might be tempted to buy cooking wines you can find on your supermarket shelves. More on Enhancing Flavors: The Basic Elements of Cooking The Truth About Cooking Wine One rule of thumb is avoiding swapping red wine when a recipe calls for white. Some wine varietals are better suited for cooking than others, which we’ll explain in a moment. This doesn’t mean you need to cook with expensive, vintage wines - save those to enjoy with your meal! It merely means that the wine you use for cooking should be drinkable. While it’s certainly okay to use wine that has been opened for a little while (up to two weeks if tightly corked), wine loses its fruity flavor over time. Heat does not improve a wine’s undesirable characteristics, either - it amplifies them. Using a cheap wine that tastes lousy or a good wine that has turned and tastes like vinegar is just going to ruin your meal. Adding wine to your dishes isn’t complicated, but don’t be tempted to pour in just any old wine – most chefs will tell you to only use wines in your cooking that you would drink. We add wine to food to intensify, accent and enhance its aromas and flavors. Convinced yet? How to Choose a Wine for Cooking With most of the alcohol removed and the healthier compounds remaining, evidence suggests you can gain the same benefits cooking with wine as with drinking it! Wine can also replace less healthy ingredients in marinades and sauces. Heating wine causes the alcohol to evaporate, especially if it cooks for 30 minutes or more. It turns out that heating wine does not remove the healthy compounds, so you could gain wine’s benefits by “eating it.” Regardless, studies have found that antioxidants and natural compounds, such as resveratrol found in red wine, can help lower cholesterol and reduce risks of diseases such as diabetes, some cancers, stroke and heart disease. If you’d prefer to avoid that, choose a wine like Cabernet Sauvignon.You’ve probably heard that drinking red wine in moderation can be beneficial for your health (although some dispute this, saying all alcohol is totally unhealthy). For sauces that could use a little sweetness, like something paired with mushrooms, this can be excellent. Note that more fruit-forward wines will become fruitier as they reduce. Pinot Noir, Merlot, or Cabernet Sauvignon. Best dry red wine for cooking beef stew or a wine-based sauce:.These bold wines will stand up well to these hearty dishes. Best red wine for braising ribs, lamb, beef roast, or another red meat:.The individual tasting notes will be cooked out and indistinguishable, which is why cooking with expensive wine is unnecessary.Īlthough most red wines will work with most recipes, here are a few tips to make it easier to find a good red wine for cooking. Most wines become more concentrated in flavor, but lose nuance, when cooked.Īcidity and fruitiness become more pronounced. But, as with all things wine-related, there are many ways to make your experience more fun and sophisticated. With those tips, you can easily start cooking with red wine. Tyrone joined The Wailers just before the age of 20, making his recording début with the band on Rastaman Vibration. On November 5, the official Wailers’ message came out as follows: "It is with great sadness and a heavy heart from the news that The Wailers’ own keyboard player, brother and friend Tyrone Downie passed away today. Many tributes have been pouring in on the death of Tyrone Downie The Wailers and friends would like to offer our heartfelt condolences to Tyrone’s family. When you hear the keys on Three Little Birds (and many other hits), you should always think of Tyrone. It reads: “It is with great sadness and a heavy heart from the news that The Wailers’ own keyboard player, brother and friend Tyrone Downie passed away. Now hear this! This week I was devastated by the news coming from Jamaica via King Isaac. Others say this shows her extreme popularity across the globe. Some fans have expressed anger at the fake report saying it was reckless, distressing and hurtful to fans of the much-loved singer. She's still alive and well.Stop believing what you see on the Internet,” they said. “She joins the long list of celebrities who have been victimized by this hoax. On Tuesday (November 8) the singer's reps officially confirmed that Rita Marley is not dead. Some pointed out that the news had not been carried on any major Jamaican networks such as radio and television, indicating that it was a fake report, as the death of a singer of Rita Marley’s stature would be major news across networks.Ī recent poll conducted for the Celebrity Post shows that 83% still think false Rita Marley death rumours are funny. Whereas some trusting fans believed the post, others were immediately skeptical of the report, perhaps learning their lesson from the huge amount of fake death reports emerging about celebrities over recent months. All players can get a new hearthstone and change the location by talking to any innkeeper.For example, Alliance players pushing for Tol'vir digsites may want to set their hearth to Desolace since there's easy ways of getting to other corners of the map via Darnassus, Theramore, Uldum, and Hyjal. In addition to the travel options below, setting your hearthstone to a good place is key-a location that's not easily accessible through other means. The "Getting To:" sections of this guide include a map with mouseover travel details, as well as tabs describing every item and method of transportation, ranging from simple town portals to elaborate portals that can only be accessed after completing quest chains. There are many varied items that can port you to special locations, like guild capes and teleport tabards.Many capital cities have portals to other capital cities-Dalaran and Vale of Eternal Blossoms have portals to major faction capitals in Azeroth, while Stormwind and Orgrimmar have portals (no questing to unlock required) for all Cataclysm zones.Recruit a Friend is great for quickly leveling characters, as there are triple experience and increased reputation gains, as well as bonus levels that can be granted to characters. With Recruit a Friend, you can summon linked characters to each other's locations anywhere in the world.This summons individual players to the stone's location. Summoning stones are also found outside major instances and raids.A warlock's Ritual of Summoning is useful for straggler players left behind-and especially getting a low-level player to an otherwise inaccessible zone. Mages can port players to capital cities, as well as teleporting themselves.You can start off riding ground mounts at level 10, increasing your travel speed and learning how to fly at later levels. We've got a page covering Riding: skill levels, mount types, speeds, and training costs.You must discover a flight path before using it for the first time-these are marked in green on your minimap. Flight paths are what most players will use to travel between nearby zones.There are numerous items, teleports, and portals that can shave minutes off your travel experience-even breadcrumb quests that you can hold onto which will provide useful ports! And which boat goes where from Stormwind anyway? Basic flight paths can take you anywhere, but they're slow and easily up to 15 minutes across a continent. Getting around Azeroth quickly is important-especially with holidays requiring lots of travel like the Lunar Festival and Love is in the Air. With the WoW transportation guide, you'll learn about all the travel options on each continent, as well as basics to flying, riding training, mage portals, and Hearthstones. |
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